A silybin-phospholipids complex counteracts rat fatty liver degeneration and mitochondrial oxidative changes
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چکیده
منابع مشابه
Biochemical changes in carbon tetrachloride fatty liver: separation of fatty changes from mitochondrial degeneration.
In 1954 Christie and Judah (3) in a study of the mechanism of action of carbon tetrachloride advanced the view that the primary locus of action of this hepatotoxin was the membranes of the liver mitochondria. Dianzani (4-6) showed that after carbon tetrachloride or phosphorus poisoning or after a choline deficient diet, there was evidence for uncoupling of oxidative phosphorylation, loss of mit...
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1. The ability of a series of compounds to uncouple oxidative phosphorylation of rat-liver mitochondria has been investigated. 2. The compounds were: 2-amino-1,1,3-tricyanopropene; carbonyl cyanide phenylhydrazone and its m-chloro and p-trifluoromethoxy derivatives; 4,5,6,7-tetrachloro-, 5-chloro-4-nitro-, 5-nitro-and 4,5,6,7-tetrachloro-1-methyl-benzotriazole; 4-hydroxy-3,5-di-iodo-, 3,5-di-br...
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We examined the subcellular localization of ACTH (adrenocorticotropic hormone)-induced changes in adrenal phospholipids using dexamethasone-treated rats. In adrenal mitochondrial fraction, ACTH significantly enhanced both concentrations and contents of phosphatidylinositol (37%), phosphatidylcholine (22%), and phosphatidylethanolamine (20%). Other mitochondrial phospholipids including cardiolip...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2013
ISSN: 1007-9327
DOI: 10.3748/wjg.v19.i20.3007